Upcoming Event

Department of Biomedical Engineering
BME Guest Speaker
"Functional Consequences of Fibroblast Loss in Tissue Homeostasis and Disease"
Michelle Tallquist, Ph.D.
Professor and Chair
Cell and Molecular Biology Graduate Program
University of Hawaii
Friday, August 2, 2019
Hosted by: Suneel Apte, MBBS, DPhil

Biomechanical Analysis of a Unique Interspinous Fixation Device Intended for Minimally Invasive Spinal Fusion.

Client: Lars Gilbertson Ph.D. / Cleveland Clinic and Bill Marras Ph.D. / The Ohio State University

Services Provided: Experiment Design / Robotic Spine Joint Testing / Data Analysis / Manuscript Preparation

Stabilization has proven to increase the fusion rates in the lumbar spine. Surgeons are continuously trying to achieve the goals of spine surgery using less invasive techniques. A new minimally invasive device has been approved to fixate two adjacent interspinous (IS) processes while the fusion occurs between the 2 vertebrae. The purpose of performing this study is to biomechanically compare different fixation systems for the stability supplementation in a Transforaminal Lumbar Interbody Fusions (TLIF). Cadaveric specimens from T12 to the sacrum were mounted to the robot. A stability comparison, through measuring the amount of motion between the instrumented vertebral segments, was done among the following scenarios: 1) intact spine, 2) TLIF, 3) TLIF with IS Fixation Device (ISD), 4) TLIF with ISD and unilateral pedicle screws, 5) TLIF with bilateral pedicle screws. The robot applied pure moment ±6Nm cycles in flexion-extension (FE), lateral bending (LB) and axial rotation (AR). The relative vertebral motion was captured using an optoelectronic camera system. The study showed that the ISD in conjunction with unilateral pedicle-screw fixation was statistically comparable to the stand alone bilateral pedicle-screw fixation in all planes of motion, flexion-extension, lateral bending and axial rotation.